The Significance of Glutathione Conjugation in Aflatoxin Metabolism
نویسندگان
چکیده
We all are exposed through air, food, drinks and skin contacts to harmful compounds throughout the period of our lifetime, including, a variety of pharmaceuticals and food-de‐ rived carcinogen metabolite (e.g. N-acetoxy-PhIP), [52], plant toxins (such as glycoalkaloids in nightshades1, cyanogenic glucosides 2, or pyrrolizidine alkaloids in some herbs and herbal teas), xenobiotics3 producing during early human pregnancy, fungal and bacterial toxins such as aflatoxins4; and cyanotoxin5; as well as free radicals and hydroperoxides. Many of these compounds are lipophilic and the organism can get rid of them only through metabolism.
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